Profhilo

Procedure overview

Profhilo treatment represents a scientific advancement in aesthetic dermatology, focusing on bio-stimulation rather than volumization. It delivers highly concentrated hyaluronic acid to rejuvenate the skin’s extracellular matrix through bioremodelling and hydration.

Medically, it promotes collagen (Type I, III) and elastin synthesis, reversing dermal aging, restoring turgor, and enhancing cutaneous resilience. Profhilo’s innovative approach bridges the gap between injectables and bioregenerative skin therapy.

Ideal candidates

Profhilo is suitable for patients experiencing early to moderate signs of skin laxity, dehydration, or dullness.

• Age Range: Typically recommended for individuals aged 30–60 showing reduced dermal elasticity.

• Skin Type Compatibility: Suitable for all phototypes; non-comedogenic and non-inflammatory by nature.
  

Procedure details

Profhilo injections are administered using the BAP (Bio Aesthetic Points) technique, a scientifically designed injection method that ensures even diffusion of the hyaluronic acid (HA) formulation across the treatment area. The BAP technique targets five specific anatomical points on each side of the face, strategically chosen to avoid major blood vessels and nerves while maximizing the spread and bio-remodeling effect of Profhilo. This approach enhances skin hydration, elasticity, and firmness with minimal risk of bruising or swelling.

The procedure typically lasts around 30 minutes, depending on the size of the treatment area. Each session involves ten precise intradermal injection points—five per side of the face, neck, or other zones being treated. The injections are placed at a depth of approximately 2–3 mm, allowing the low-viscosity HA to disperse naturally through the tissue layers for uniform biostimulation of collagen and elastin.

Anesthesia is generally not required, as the procedure is quick and well tolerated. However, for patients with low pain thresholds or sensitive skin, a topical numbing cream may be applied 15–20 minutes prior to treatment to ensure maximum comfort. The ultra-fine needles used further minimize discomfort and downtime, allowing most patients to resume daily activities immediately after the session.

Overall, the BAP technique ensures precise placement, optimal diffusion, and consistent rejuvenation results, making Profhilo a leading non-surgical option for improving skin quality and restoring youthful radiance.

Procedure details

Profhilo injections are administered using the BAP (Bio Aesthetic Points) technique, a scientifically designed injection method that ensures even diffusion of the hyaluronic acid (HA) formulation across the treatment area. The BAP technique targets five specific anatomical points on each side of the face, strategically chosen to avoid major blood vessels and nerves while maximizing the spread and bio-remodeling effect of Profhilo. This approach enhances skin hydration, elasticity, and firmness with minimal risk of bruising or swelling.

The procedure typically lasts around 30 minutes, depending on the size of the treatment area. Each session involves ten precise intradermal injection points—five per side of the face, neck, or other zones being treated. The injections are placed at a depth of approximately 2–3 mm, allowing the low-viscosity HA to disperse naturally through the tissue layers for uniform biostimulation of collagen and elastin.

Anesthesia is generally not required, as the procedure is quick and well tolerated. However, for patients with low pain thresholds or sensitive skin, a topical numbing cream may be applied 15–20 minutes prior to treatment to ensure maximum comfort. The ultra-fine needles used further minimize discomfort and downtime, allowing most patients to resume daily activities immediately after the session.

Overall, the BAP technique ensures precise placement, optimal diffusion, and consistent rejuvenation results, making Profhilo a leading non-surgical option for improving skin quality and restoring youthful radiance.

Costs and insurance

Profhilo is an elective aesthetic procedure and not covered by insurance policies. Costs vary by practitioner expertise and session frequency.

• Average Cost Range: ₹25,000–₹45,000 per session in India, with most patients requiring two sessions four weeks apart.

• Insurance Coverage: Excluded under non-medically necessary treatments, except when used adjunctively in dermatologic repair.
  

Benefits

Profhilo treatment benefits extend beyond hydration, it restructures and strengthens skin integrity through cellular stimulation.

• Hydration Enhancement: Deep dermal hydration improves suppleness, radiance, and tactile smoothness.

• Tissue Tightening: Induces neo-collagenesis and elastogenesis for firmer, lifted, and more youthful-looking skin.
  

Risks and complications

Profhilo is clinically safe when performed by qualified professionals; however, minor side effects can occur.

• Injection Reactions: Transient erythema, mild swelling, or papules that resolve within 24–48 hours.

• Rare Complications: Infection or hypersensitivity due to improper aseptic technique or injection depth.
  

Patient experiences

Recovery after Profhilo injection is minimal, allowing patients to resume normal activity almost immediately.

• Post-Procedure Care: Avoid makeup, exercise, and heat exposure for 24 hours post-injection.

• Visible Improvement: Noticeable radiance and skin firmness within 7–10 days after the first session.
  
  

Expert opinions

Dermatologists and aesthetic physicians recognize Profhilo as a leading bio-stimulatory innovation for age-related skin changes.

• Clinical Validation: Supported by histological studies demonstrating increased fibroblast activity and collagen density.

• Professional Consensus: Experts highlight its safety and versatility as a preventive and corrective treatment for early aging.

Regulatory and ethical considerations

Profhilo treatments must comply with local medical device regulations and be administered by licensed professionals.

• Regulatory Classification: CE-marked medical device approved for aesthetic injection use.

• Ethical Standard: Practitioners must disclose realistic outcomes, risks, and procedural expectations to patients.
  

Technological advancements

Profhilo incorporates patented NAHYCO Hybrid Technology, creating a dual-action system that hydrates and remodels the skin matrix.

• NAHYCO Complex: Combines high (H-HA) and low (L-HA) molecular weight HA for sustained tissue integration.

• Thermal Stability: Ensures longevity and reduced degradation compared to traditional hyaluronic acid injectables.
  

Alternative treatment

For patients seeking other bio-rejuvenation or lifting solutions, several alternatives exist:

1. Dermal Fillers: Provide volumization and contour correction, targeting deeper structural deficits.

2. Skin Boosters (e.g., Restylane Vital): Focus on hydration and superficial dermal quality improvement.

3. PRP Therapy: Uses autologous platelet growth factors for collagen induction and wound healing.
   

Disclaimer

This information is intended for educational purposes only and should not replace professional consultation. Patients must seek evaluation from a board-certified dermatologist or aesthetic physician before undergoing Profhilo or similar injectable treatments.

Conclusion

Profhilo treatment embodies the evolution of modern bio-aesthetic medicine—merging hydration, collagen regeneration, and non-invasive rejuvenation into one scientifically designed injectable. Safe, effective, and naturally enhancing, it restores youthfulness without altering facial identity.

At Cosma Beauty, we connect patients with board-certified dermatologists and aesthetic specialists. By integrating clinical expertise, evidence-based protocols, and individualized attention, we prioritize safety, natural results, and patient confidence, ensuring every treatment reflects excellence, precision, and authenticity.

FAQs

1. How many Profhilo sessions are needed for optimal results?

Typically, two sessions spaced four weeks apart are recommended, followed by maintenance every six months.

2. How does Profhilo differ from dermal fillers?

Unlike fillers, Profhilo does not add volume; it rejuvenates the skin by stimulating collagen and elastin for a natural, hydrated glow.

3. Can Profhilo be combined with other aesthetic procedures?

Yes, it complements treatments such as botulinum toxin, laser resurfacing, and microneedling without interference.

4. Are Profhilo results immediate?

Mild improvement in hydration appears within days, with full bio-remodeling effects visible after the second session.

5. What areas can be treated with Profhilo?

Common sites include face, neck, décolletage, upper arms, and hands for overall rejuvenation.

6. What are Profhilo before and after results like?

Clinical images show smoother, more hydrated skin with improved elasticity and subtle tightening without volume distortion.